Hydrolytically stable polyurethanes

Plastic-PDMS bonding for high pressure hydrolytically stable active microfluidics.

We explore the application of organofunctional silanes for bonding plastic substrates to PDMS membranes. Such devices would enable actuated membrane microfluidics in plastic devices. Bond strength degradation in aqueous environments can be reduced by using bis-silanes with larger alkoxy end groups to promote organofunctional bond formation with the plastic substrate. Hydrolytic failure can also...

Hydrolytically Stable Analogues of Sugar Phosphates and a Miniaturized in Situ Enzymatic Screen

Thermally/hydrolytically stable covalent organic frameworks from a rigid macrocyclic host.

Two new 2D COFs were synthesized from triformylcyclotrianisylene, which show not only thermal stability but also hydrolytic stability. CTV-COF-1 with smaller pore size stored a high hydrogen level of 1.3 wt% at low pressure, while CTV-COF-2 with larger pore size showed superior carbon dioxide uptake, up to 250 cm(3) g(-1) at 298 K and 50 bar.

Plastic-pdms Hybrid Devices for High Pressure Hydrolytically Stable Active Microfluidics

Active devices such as pumps and mixers have been fabricated in plastic-PDMS hybrid devices. By utilizing functionalized silane primers, bond strength between Polycarbonate or PMMA and PDMS improved in dry and aqueous environments. Plastic-primer-PDMS layers exposed to acid and base solutions at 70 C for 2 hours showed no signs of delamination at 30 psi for pH -1 to 15 and 60 psi for pH 0 to 15...

Hydrolytically stable octahedral silicon complexes as bioactive scaffolds: application to the design of DNA intercalators.

We here introduce octahedral silicon serving as a structural center for the design of hydrolytically stable bioactive complexes as demonstrated with the generation of silicon-based high affinity DNA binders. This proof-of-principle study suggests that octahedral silicon complexes are falsely neglected, promising structural templates for widespread applications in chemical biology and medicinal ...